Crystal structure of hcv ns5b polymerase with a novel benzisothiazole inhibitor
收藏Protein Data Bank Japan2024-04-03 更新2026-03-21 收录
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Crystal structure of hcv ns5b polymerase with a novel benzisothiazole inhibitor Descriptor: (5S)-1-benzyl-3-(1,1-dioxido-1,2-benzisothiazol-3-yl)-4-hydroxy-5-(1-methylethyl)-1,5-dihydro-2H-pyrrol-2-one, RNA-directed RNA polymerase Authors: Han, Q, Showalter, R.E, Zhao, Q, Kissinger, C.R. Deposit date: 2008-05-07 Release date: 2009-05-19 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase. Bioorg.Med.Chem.Lett., 18, 2008
创建时间：
2008-05-07
