The plasma of 5-Fluorouracil (5-FU) (100 mg/kg, i.v.) pharmacokinetics in rats treated with and without MMP-8 inhibitor then delivered to whole pelvic irradiation with 2 Gy.
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AUC: area under the plasma concentration vs. time curve; t1/2: terminal elimination phase half-life; Cmax: maximum observed plasma concentration; MRT: mean residence time; CL: total plasma clearance; Vss: volume of distribution at steady state.*The mean difference is significant at the 0.05 level in comparison to the whole pelvic irradiation with solvent and 5-FU group.
创建时间：
2015-12-02
