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Super-enhancer RNA seRNAHP promotes liver regeneration via upregulation of phosphoglycerate dehydrogenase and serine biosynthesis

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NIAID Data Ecosystem2026-05-10 收录
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A 70% partial hepatectomy (PHx) was performed on male super-enhancer Nacc1-SE (located near the Nacc1 gene) knockout mice to evaluate the contribution of Nacc1-SE to liver regeneration. In vitro, primary mouse hepatocytes and Hepa1-6 cells were used to investigate the underlying mechanisms of Nacc1-SE in modulating PHx.

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2025-11-22
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