DNA replication and DSB factor binding in the meiotic S-phase checkpoint in budding yeast

During gamete formation, crossover recombination must occur on replicated DNA to ensure proper chromosome segregation in the first meiotic division在配子发生过程中，已复制的DNA上必须发生交叉重组（crossover recombination），以确保减数第一次分裂时染色体能够正确分离。