S1 File -

Contains all collected data that were the basis of all statistical analyses, organized according to the figures, in the following order: Fig 1. Heart rate in the three experimental groups (Panel A: heart rate from invasive measurement (pressure); Panel B: heart rate from cardiac ultrasonography). Fig 2. Heart parameters assessed by cardiac ultrasonography (Panel A: end-systolic volume; Panel B: end-diastolic volume; Panel C: end-diastolic volume). Fig 3. Acetylcholine-induced relaxation ability of isolated thoracic aorta segments after epinephrine precontraction. Fig 4. Systemic and cardiovascular oxidative-nitrative stress (Panel A. MDA; Panel B.Cardiac (left ventricular) oxidative stress detected by 4-hydroxy-noneal staining; Panel C. 4-hydroxy-noneal staining of the aorta; Panel E. Assessing nitrative stress. 3-nitrotyrosine staining in the aorta; Panel G. PAR staining of the aorta). Fig 5. Histological changes of the vasoactive markers in the thoracic aorta (Panel A. eNOS staining of the endothelium; Panel C. COX-2 staining of the endothelium; Panel E. cGMP in the aortic wall). Fig 6. Histological changes of the Cannabinoid receptor 1. and 2. intensity in the thoracic aorta (CB1R; CB2R).
(XLSX)