A single amino acid substitution improves the in vivo immunogenicity of the HPV16 oncoprotein E7(11-20) cytotoxic T lymphocyte epitope.
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资源简介：
Immunization with the epitope produced an epitope-specific response. In further experiments, immunization with an altered peptide ligand (YMLDLQPETV) of the naturally-occurring epitope (YMLDLQPETT) was shown to produce an enhanced response against the naturally-occurring epitope. Similar results were obtained whether or not the effector cells were restimulated in vitro prior to the assay.
提供机构：
IEDB
创建时间：
2005-01-01
