Co(III)-Catalyzed Regioselective Functionalization of Isoquinolones with Naphthoquinones
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https://figshare.com/articles/dataset/Co_III_-Catalyzed_Regioselective_Functionalization_of_Isoquinolones_with_Naphthoquinones/25958898
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资源简介：
A strategy
for Co(III)-catalyzed C(sp2)–H
alkenylation
of N-protected isoquinolones with 1,4-naphthoquinones
has been disclosed. The developed protocol was efficiently applied
for diversely substituted isoquinolones. Preliminary mechanistic experiments
revealed the involvement of a five-membered cobaltacycle as an intermediate.
Deuterium labeling experiments suggested the reversible nature of
the C–H activation step. The scale-up reaction was also carried
out, and the product was utilized as a chemosensor to detect Fe3+ ions.
创建时间：
2024-06-03
