Crystal structure of human BACE-1 bound to Compound 24B
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Crystal structure of human BACE-1 bound to Compound 24B Descriptor: (4aR,8aS)-8a-(2,4-difluorophenyl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine, Beta-secretase 1 Authors: Vajdos, F.F, Parris, K. Deposit date: 2014-11-14 Release date: 2015-03-04 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design. J.Med.Chem., 58, 2015
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2014-11-14
