Sensitivity and specificity of the drug resistance detection HRM assays.

a[Number of drug-resistant isolates with mutations]/[number of drug-resistant isolates with mutations+number of drug-resistant isolates without mutation].
bStatistical calculations were performed with the free software available from http://www.measuringusability.com/wald.htm using the Adjusted Wald method.
c[Number of drug-susceptible isolates without mutations]/[number of drug-susceptible isolates with mutations+number of drug-susceptible isolates without mutation].