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Human Cyclophilin D in complex with norbornane fragment derivative

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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Human Cyclophilin D in complex with norbornane fragment derivative Descriptor: 14-ethyl-4,6-dioxa-10,14-diazatricyclo[7.6.0.0^{3,7}]pentadeca-1(9),2,7-trien-13-one, 2-[(1~{R},2~{R},6~{S},7~{S})-3,5-bis(oxidanylidene)-4-azatricyclo[5.2.1.0^{2,6}]decan-4-yl]ethanoic acid, DI(HYDROXYETHYL)ETHER, ... Authors: Graedler, U. Deposit date: 2019-04-05 Release date: 2019-11-27 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of novel Cyclophilin D inhibitors starting from three dimensional fragments with millimolar potencies. Bioorg.Med.Chem.Lett., 29, 2019

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2019-04-05
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