This pipeline was created with the open-source software CellProfiler (4.2.1 release) and it is suitable for the automatized analysis of confocal microscopy images, allowing the quantification of the l
S1i represents signal intensity of pixels in the channel 1 and S2i represents signal intensity of pixels in the channel 2; S1mean and S2mean reflect the average intensities of these respective channel
Contains Figures S1–S4. Figure S1, Z-stack analysis of co-localisation between PS1-GFP and LRP-dsRed. Figure S2, co-localisation between BACE1-GFP and LRP-dsRed as ascertained by z-stack analysis. Fig