The structure of the polo-box domain (PBD) of Plk1 in complex with Z228588490
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The structure of the polo-box domain (PBD) of Plk1 in complex with Z228588490 Descriptor: (3~{R},5~{R})-1-[2,4-bis(fluoranyl)phenyl]-5-oxidanyl-pyrrolidine-3-carboxylic acid, Serine/threonine-protein kinase PLK1 Authors: Kunciw, D.L, Rossmann, M, Stokes, J.E, De Fusco, C, Spring, D.R, Hyvonen, M. Deposit date: 2017-04-07 Release date: 2018-02-21 Last modified: 2026-05-13 Method: X-RAY DIFFRACTION (1.81 Å) Cite: A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation. Sci Rep, 9, 2019
创建时间：
2017-04-07
