Dissociation of biochemical and antiretroviral activities of Integrase-LEDGF Allosteric Inhibitors revealed by resistance of A125 polymorphic HIV-1
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Dissociation of biochemical and antiretroviral activities of Integrase-LEDGF Allosteric Inhibitors revealed by resistance of A125 polymorphic HIV-1 Descriptor: Integrase, MAGNESIUM ION Authors: Ruff, M, Benarous, R. Deposit date: 2017-07-18 Release date: 2018-03-07 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure-function analyses unravel distinct effects of allosteric inhibitors of HIV-1 integrase on viral maturation and integration. J. Biol. Chem., 293, 2018
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2017-07-18
