Gene expression levels in the hypothalamus of mice with low weight gain

The difference in body weight among individuals is associated with metabolic differences that affect various physiological processes. Therefore, the characterization of mice with low-weight gain may help identify potential targets for anti-obesity measures and therapeutic interventions for metabolic diseases. In this study, we aimed to find common features between three types of mice genetically knockout to exhibit low-weight gain, G protein-coupled receptor, family C, group 5, member B (Gprc5b), gastric inhibitory polypeptide receptor (Gipr), and Iroquois related homeobox 3 (Irx3).