Changes in pain intensity between baseline and 1 month after patch application presented as SPID for capsaicin and placebo patch treatments, and the mean difference.

The SPID was calculated as the difference between the baseline SPI-value and the SPI-value at 1 month after patch application. Each SPI- value contains six median values (pain assessments twice daily for three days). Values are mean (95% CI). Positive values of SPID indicate pain reduction after treatment. P-values indicate comparisons of SPID (capsaicin vs. placebo).NRS = Numerical Rating Scale (0–10), SPID = Summed pain intensity difference, SPI = summed pain intensity.Changes in pain intensity between baseline and 1 month after patch application presented as SPID for capsaicin and placebo patch treatments, and the mean difference.