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Three-Component Assembly of Conjugated Enyne Scaffolds via <i>E</i>-Selective Olefination of Ynals

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NIAID Data Ecosystem2026-03-07 收录
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Benefited by the accessible ynamido–lithium intermediates Ib from a Cu-catalyzed azide–alkyne cycloaddition in the presence of stoichiometric amounts of LiOH, a mild and flexible three-component route to conjugated enyne scaffolds was successfully achieved via a formal E-selective olefination strategy.

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2016-02-20
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