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Development of a 2-Aza-Cope-[3 + 2] Dipolar Cycloaddition Strategy for the Synthesis of Quaternary Proline Scaffolds

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https://figshare.com/articles/dataset/Development_of_a_2_Aza_Cope_3_2_Dipolar_Cycloaddition_Strategy_for_the_Synthesis_of_Quaternary_Proline_Scaffolds/2735905
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A one-pot multicomponent procedure for the synthesis of highly functionalized pyrrolidine rings through a domino 2-aza-Cope-[3 + 2] dipolar cycloaddition sequence has been demonstrated. This protocol was found to be both high-yielding and stereoselective for the endo cycloadduct.
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2010-09-03
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