Development of a 2-Aza-Cope-[3 + 2] Dipolar Cycloaddition Strategy for the Synthesis of Quaternary Proline Scaffolds
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A one-pot multicomponent procedure for the synthesis of highly functionalized pyrrolidine rings through a domino 2-aza-Cope-[3 + 2] dipolar cycloaddition sequence has been demonstrated. This protocol was found to be both high-yielding and stereoselective for the endo cycloadduct.
创建时间：
2010-09-03
