Massive parallel single cell RNA Sequencing of human embryos reveals novel dynamic changes across development stages

Preimplantation human embryonic development is a highly dynamic cellular and molecular process, the correct execution of which is critical for successful development to occur. However the mechanism of this event remains largely unknown due to the scarcity of the material, legal restraints and limited techniques to faithfully analyze small amounts of samples. The development of single cell RNA-seq technology to measure gene expression at single cell levels opens new avenues for investigations into preimplantation human embryonic development.