Proteasome inhibition blocks estrogen-dependent gene transcription by decreasing histone H2B monoubiquitination in human breast cancer cells. Homo sapiens

蛋白酶体抑制

The estrogen receptor-alpha (ERα) determines breast cancer cell phenotype and is a prognostic indicator. A better understanding of the mechanisms controlling ERα function may uncover improved strategi

NIAID Data Ecosystem50

E-GEOD-43714

基因表达调控

蛋白酶体抑制

Microarray to find ATF5 dependent genes in response to proteasome inhibition

NIAID Data Ecosystem40

Proteasome inhibition and oxidative biochemistry are synergistic triggers of metabolic heme toxicity (part 2)

血红素毒性机制

蛋白酶体抑制

Control of intracellular heme levels by extracellular scavenger proteins and intracellular heme oxygenases are essential functions during disease states with enhanced extracellular heme release. Durin

NIAID Data Ecosystem30

Proteasome inhibition and oxidative biochemistry are synergistic triggers of metabolic heme toxicity

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