Human IMPDH2 treated with ATP, IMP, and 20 mM GTP. Fully compressed filament end reconstruction.
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Human IMPDH2 treated with ATP, IMP, and 20 mM GTP. Fully compressed filament end reconstruction. Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... Authors: Johnson, M.C, Kollman, J.M. Deposit date: 2019-09-19 Release date: 2020-03-25 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (3.27 Å) Cite: Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation. Elife, 9, 2020
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2019-09-19
