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Palladium-Catalyzed Diastereoselective Oxyarylation of 2‑Alkylindoles

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Figshare2016-02-15 更新2026-04-29 收录
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Diastereoselective oxyarylation of N-protected 2-alkylindoles with commercially available boronic acids and TEMPO as a mild oxidant to give N-protected 2-aryl-2-alkyl-3-(2-chloroacetoxy)­indolines is described. Reactions are easy to conduct, and product indolines containing a fully substituted C-center are obtained in good yields with good to excellent selectivities.

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2016-02-15
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