Copy of Silver‑doped phosphate coacervates as observed by Neutron Compton Scattering and Resonance Capture Analysis

Wound management is a major area of global unmet need. Growing elderly and diabetic populations are leading to a sharp increase in the cases of chronic wounds (diabetic foot, venous, and pressure ulcers). A large proportion of these wounds are resistant to current treatments, remaining unhealed for months or years, making chronic wounds a substantial economic, social and clinical challenge. There is a great demand from patients requiring skin repair, as a result of poorly healed acute wounds or chronic wounds. Therefore, there is an urgent need for new materials that could rapidly stimulate the healing process and simultaneously prevent infections. Phosphate‑based coacervates (PC) have been the subject of increased interest due to their great potential in tissue regeneration and as controlled delivery systems. In order to investigate the local structure and dynamics of 0.1 mol% Ag-doped PC samples, NCS and NRCA will be employed on VESUVIO at room temperature.