Diazabicyclooctenone ETX2514 bound to Class D beta lactamase OXA-24 from A. baumannii

Diazabicyclooctenone ETX2514 bound to Class D beta lactamase OXA-24 from A. baumannii Descriptor: (2S,5R)-1-formyl-4-methyl-5-[(sulfooxy)amino]-1,2,5,6-tetrahydropyridine-2-carboxamide, (2S,5R)-4-methyl-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]oct-3-ene-2-carboxamide, Beta-lactamase, ... Authors: Olivier, N.B, Lahiri, S. Deposit date: 2017-04-07 Release date: 2017-06-07 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (1.93 Å) Cite: ETX2514 is a broad-spectrum beta-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii. Nat Microbiol, 2, 2017