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Supporting data for ''Synthetic and Chemical Biology Studies of Pseudaminic Acid and Acinetaminic Acid''

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datahub.hku.hk2023-06-26 更新2025-01-15 收录
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https://datahub.hku.hk/articles/dataset/Supporting_data_for_Synthetic_and_Chemical_Biology_Studies_of_Pseudaminic_Acid_and_Acinetaminic_Acid_/23434742/1
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The structural complexity of pseudaminic acid and acinetaminic acid makes them difficult to be obtained either by isolation from natural sources or by chemical syntheses reported previously, which limits the further study of their biological functions and developing related therapeutic approaches. Therefore, I spend efforts to focus on the synthetic and chemical biology studies of pseudaminic acid and acinetaminic acid. This file covers all the NMR spectra of the synthetic study of pseudaminic acid and acinetaminic acid in my thesis, including 1H, 13C, COSY, HMBC and HSQC NMR spectra. And the NMR spectra were collected via Advance DRX Bruker 400, 500 and 600 MHz spectrometers and analyzed via MestReNova software.

伪氨基酸和醋酸氨基的分子结构复杂,导致其获取途径受限,无论是从天然来源分离还是通过之前报道的化学合成方法,这限制了对其生物学功能的研究及其相关治疗方法的开发。因此,我致力于对伪氨基酸和醋酸氨基的合成与化学生物学研究。本文件涵盖了我在论文中对伪氨基酸和醋酸氨基合成研究中的所有核磁共振光谱,包括1H、13C、COSY、HMBC和HSQC核磁共振光谱。这些光谱是通过Bruker 400、500和600 MHz的Advance DRX核磁共振光谱仪收集的,并使用MestReNova软件进行分析。
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