Appropriateness of antibiotic prescription for prophylactic purpose among Italian dental practitioners: results from a cross-sectional study

The dataset was used in a cross-sectional study primarily aimed to to investigate the pattern of antibiotic prescription for prophylaxis purposes among Italian DPs.
From April to October 2019, a nationwide cross-sectional study was conducted in a representative sample of the Italian general and specialist DPs. The information is collected through a mixed technique, which uses an online questionnaire that is filled in by respondents, a direct telephone interview with the questionnaire administered by an interviewer, and a self-administered paper questionnaire.
A structured questionnaire was used, comprising of four sections: (1) an introductory section presenting study aims and motivation at the end of which DPs could give their written consent in joining the study; (2) a socio-demographic data collection section; (3) the main research section about practices regarding prophylactic antibiotic prescriptions; (4) and sources of information used to update knowledge on antibiotic use in dental practices. Bivariate (t-tests, chi-square and Fisher exact test) and multivariate analyses were conducted to examine the potential association with the DP correct prescription practice. Moreover, a logistic regression model was used to estimate the odds of correct prescription practice depending on the invasive dental procedures and the presence of indication or not. The interaction between the two factors was also investigated.
563 DPs answered the general questionnaire (response rate 52.6%).

本数据集应用于一项横断面研究，其主要目标在于探究意大利牙科执业医师（DP）在预防性目的下开具抗生素处方的模式。2019年4月至10月间，于意大利全国范围内对具有代表性的普通及专科牙科执业医师群体进行了横断面研究。数据收集采用混合技术，包括由受访者填写的在线问卷、由调查员主持的直接电话访谈问卷，以及自行填写的纸质问卷。问卷结构严谨，分为四个部分：（1）引言部分，介绍研究目的与动机，并在文末提供DP书面同意加入研究的选项；（2）社会学人口统计数据收集部分；（3）关于预防性抗生素处方实践的主要研究部分；（4）以及用于更新牙科实践中抗生素使用知识的资讯来源。通过双变量分析（t检验、卡方检验和Fisher确切检验）和多变量分析，考察了与DP正确处方实践潜在关联的可能性。此外，采用逻辑回归模型估算正确处方实践的概率，取决于侵入性牙科手术及是否存在指征。同时，亦对两个因素的交互作用进行了研究。共有563位DP回答了通用问卷（响应率为52.6%）。