Cryo-EM structure of the setmelanotide-bound human melanocortin receptor 4 (MC4R)-Gq complex
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Cryo-EM structure of the setmelanotide-bound human melanocortin receptor 4 (MC4R)-Gq complex Descriptor: CALCIUM ION, G subunit q (Gi1-Gq chimeric), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Feng, W.B, Zhou, Q.T, Wang, M.W. Deposit date: 2025-12-17 Release date: 2026-08-12 Last modified: 2026-08-26 Method: ELECTRON MICROSCOPY (3.11 Å) Cite: Rationale of renewed efforts in developing MC4R modulators to treat metabolic disorders. Acta Pharm Sin B, 16, 2026
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2025-12-17
