AMYLOIDOGENIC LIGHT CHAINS IMPAIR PLASMA CELL SURVIVAL

NIAID Data Ecosystem2026-05-01 收录

淀粉样变性机制

浆细胞生物学

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE176119 数据链接链接失效反馈

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资源简介：

We used lentiviral vectors to generate cell lines expressing LCs from patients suffering from AL amyloidosis. Compare AL LC to MM LC

创建时间：

2023-08-31

Crystal structure of human transthyretin variant A25T in complex with thyroxine (T4)

蛋白质晶体学

淀粉样变性机制

Crystal structure of human transthyretin variant A25T in complex with thyroxine (T4) Descriptor: 3,5,3',5'-TETRAIODO-L-THYRONINE, Transthyretin Authors: Lima, L.M.T.R, Palmieri, L.C, Foguel, D, Palhan

Protein Data Bank Japan2023-11-15 更新80

Neutron structure of human transthyretin (TTR) T119M mutant at room temperature to 1.85A resolution

蛋白质结构解析

淀粉样变性机制

Neutron structure of human transthyretin (TTR) T119M mutant at room temperature to 1.85A resolution Descriptor: Transthyretin Authors: Yee, A.W, Moulin, M, Blakeley, M.P, Ostermann, A, Cooper, J.B, Ha

Protein Data Bank Japan2024-05-01 更新50

Understanding Heterogeneity of Human Bone Marrow Plasma Cell Maturation and Survival Pathways by Single Cell Analyses [scVDJ-seq]

单细胞转录组学

浆细胞生物学

Human bone marrow (BM) plasma cells are heterogeneous, ranging from newly arrived antibody-secreting cells (ASC) to long-lived plasma cells (LLPC). We provide single cell transcriptional resolution of

NIAID Data Ecosystem30

Exercise suppresses mouse systemic AApoAII amyloidosis through enhancement of the p38 MAPK signaling pathway. Exercise suppresses mouse systemic AApoAII amyloidosis through enhancement of the p38 MAPK signaling pathway

淀粉样变性机制

运动干预分子药理学

Exercise interventions are beneficial for reducing the risk of age-related diseases, including amyloidosis, but the underlying molecular links remain unelucidated. Here, we investigated the protective

NIAID Data Ecosystem50

Immunoglobulin light chain variable domain AL-T05

蛋白质结构解析

淀粉样变性机制

Immunoglobulin light chain variable domain AL-T05 Descriptor: ACETATE ION, ALT-05 immunoglobulin light chain variable domain from light chain amyloidosis patient, ZINC ION Authors: Ramirez-Alvarado, M

Protein Data Bank Japan2024-11-20 更新30

AMYLOIDOGENIC LIGHT CHAINS IMPAIR PLASMA CELL SURVIVAL

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