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Radicicol analogues bound to the ATP site of HSP90

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Protein Data Bank Japan2023-12-13 更新2026-03-21 收录
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Radicicol analogues bound to the ATP site of HSP90 Descriptor: (5Z)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 Authors: Roe, S.M, Prodromou, C, Pearl, L.H. Deposit date: 2006-07-04 Release date: 2006-11-30 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Inhibition of Hsp90 with Synthetic Macrolactones: Synthesis and Structural and Biological Evaluation of Ring and Conformational Analogs of Radicicol. Chem.Biol., 13, 2006

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2006-07-04
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