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Effect of polymorphic Y chromosomes on XXY females. Drosophila melanogaster

NIAID Data Ecosystem2026-03-06 收录

果蝇性别决定

染色体异常表达谱

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA129955 数据链接链接失效反馈

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资源简介：

see publication, arrays from 4 XXY genotypes containing polymorphic Y chromosomes Overall design: Dye swaps, loop design.

应用场景：

创建时间：

2010-10-02

果蝇性别决定

性腺发育转录组学

Drosophila sex determination and gonadal development is regulated at both the pre-mRNA splicing level, by the RNA-binding protein encoded by transformer (tra), and at the transcriptional level by the

NIAID Data Ecosystem30

Structure and Novel Functional Mechanism of Drosophila SNF in Sex-Lethal Splicing

RNA剪接调控

果蝇性别决定

Sans-fille (SNF) is the Drosophila homologue of mammalian general splicing factors U1A and U2B″, and it is essential in Drosophila sex determination. We found that, besides its ability to bind U1 snRN

NIAID Data Ecosystem30

eIF4e and snf interactions with Sxl.

果蝇性别决定

突变体存活率分析

Females heterozygous for the indicated mutation(s) were crossed to Sxlf1, Sxl7BO or Sxlf9 males at 29°C. Female viability was calculated as ((#females)/(#males))100 except in crosses with snf mutation

NIAID Data Ecosystem20

Chinmo prevents transformer alternative splicing to maintain male sex identity

果蝇性别决定

剪接机制调控

Reproduction in sexually dimorphic animals relies on successful gamete production, executed by the germline and aided by somatic support cells. Somatic sex identity in Drosophila is instructed by sex-

NIAID Data Ecosystem30

Identification of transcripts whose abundance changes in response to acute switches in DSX isoform in the ovary and testis. Drosophila melanogaster

果蝇性别决定

基因表达调控

RNAseq of dissected adult ovary and testis after DSX isoform is switched using temperature inducible alleles or constructs. Overall design: Biological duplicates were sequenced for each genotype at ea

NIAID Data Ecosystem20

Effect of polymorphic Y chromosomes on XXY females. Drosophila melanogaster

资源简介：

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