Table_1_Work stress and changes in heart rate variability among employees after first acute coronary syndrome: a hospital-based longitudinal cohort study.DOCX

BackgroundWork stress is considered as a risk factor for coronary heart disease, but its link with heart rate variability (HRV) among heart attack survivors is unknown yet. The aim of this study was to investigate associations between baseline work stress and the changes of HRV over one-year after onset of acute coronary syndrome (ACS).MethodsHundred and twenty-two patients with regular paid work before their first ACS episode were recruited into this hospital-based longitudinal cohort study. During hospitalization (baseline), all patients underwent assessments of work stress by job strain (JS) and effort-reward imbalance (ERI) models, and were assigned into low or high groups; simultaneously, sociodemographic and clinical data, as well depression, anxiety, and job burnout, were collected. Patients were followed up 1, 6, and 12 months after discharge, with HRV measurements at baseline and each follow-up point. Generalized estimating equations were used to analyze the effects of baseline work stress on HRV over the following 1 year.ResultsAfter adjusting for baseline characteristics and clinical data, anxiety, depression, and burnout scores, high JS was not associated with any HRV measures during follow-up (all p > 0.10), whereas high ERI was significantly related to slower recovery of 5 frequency domain HRV measures (TP, HF, LF, VLF, and ULF) (all p

背景工作压力被视为冠心病的风险因素，但其与心肌梗死幸存者心率变异性（HRV）之间的联系尚不清楚。本研究的目的是调查基线工作压力与急性冠状动脉综合征（ACS）发作后一年内心率变异性（HRV）变化之间的关联。方法：招募了122名在首次ACS发作前有规律有偿工作的患者参与这项基于医院的纵向队列研究。在住院期间（基线），所有患者通过工作压力的作业压力（JS）和努力-回报失衡（ERI）模型进行评估，并被分为低风险或高风险组；同时，收集了社会学人口统计学和临床数据，以及抑郁、焦虑和工作倦怠等信息。患者在出院后1个月、6个月和12个月进行随访，并在基线和每个随访点进行心率变异性测量。使用广义估计方程分析了基线工作压力对随后的1年内心率变异性（HRV）的影响。结果：在调整基线特征和临床数据、焦虑、抑郁和倦怠评分后，高风险作业压力在随访期间与任何心率变异性指标均无关联（所有p值均大于0.10），而高风险的努力-回报失衡与5个频率域心率变异性指标（TP，HF，LF，VLF和ULF）的恢复速度减慢显著相关（所有p值均小于0.05）。