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Multicomponent Synthesis of Diverse o‑Arylated Benzamides via o‑Aminophenol (OAP) Directed C(sp2)‑H Arylation

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Figshare2017-08-17 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Multicomponent_Synthesis_of_Diverse_i_o_i_Arylated_Benzamides_via_i_o_i_Aminophenol_OAP_Directed_C_sp_sup_2_sup_H_Arylation/5318326
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o-Aminophenol (OAP) has been discovered as practical precursor of directing group (DG) in the palladium-catalyzed aromatic C–H arylation of benzamides. This newly identified, simple, and low cost DG has exhibited broad substrate tolerance in the rapid synthesis of various o-arylated benzamides via direct assemblies of benzoyl chlorides, aryl iodides, and different o-aminophenols in the form of step economical multicomponent reaction.
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2017-08-17
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