Gene expression profile at single cell level of tumor cells and immune cells from mouse SCLC tumors and preSC allograft samples.. Gene expression profile at single cell level of tumor cells and immune cells from mouse SCLC tumors and preSC allograft samples.

Small cell lung carcinoma (SCLC) is a lethal neuroendocrine type of lung cancer with limited therapeutic options. We used single cell RNA sequencing (scRNA-seq) to study SCLC tumogenesis. Overall design: We used a gene knockout induced SCLC mouse model and a mouse cell line allograft model. Collect the fresh tissue and analyzed using scRNAseq.