These genes were not previously known to generate resistance, yet their resistance function was confirmed when the ORFs encoding them were cloned into E. coli.
a: http://ccb.bmi.ac.cn/sRNAtarget[28].b: http://rna.informatik.uni-freiburg.de:8080/IntaRNA.jsp[29].c: list of genes is in Table S2.d: cut-off e: cut-off
These genes were not previously known to generate resistance, yet their resistance function was confirmed when the ORFs encoding them were cloned into E. coli.
aThe genes acm, pilA, pilB and sagA are prevalent among all E. faecium strains; the genes EfmE4452_1561 and EfmE4452_1565 are uniquely present in community ARE isolates (this paper). All other genes a