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The ERL-resistant HCC827 cells lines are tumorigenic.

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Figshare2016-02-23 更新2026-04-29 收录
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A) Soft agar colonies were counted by ImageJ software. The percentage of colony forming efficiency (CFE) of parental (P) and ERL-resistant cell lines, as mean ± s.e.m., is shown. Histograms in gray and white colors indicate respectively vehicle (DMSO, 0.01%) and ERL (erlotinib 1 μM) cell treatments; B) Tumor volume of xenograft nodes, calculated as described in material and methods, are shown as mean ± s.e.m; C) Times to four (4x) and six fold (6x) increases from initial tumor volumes (day 3) are shown respectively by white and grey bars. P-values

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2016-02-23
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