Susceptibility of c14dm− mutants to ITZ and Amp B.
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L. major WT or c14dm− promastigotes were inoculated in M199 medium at 2.0×105 cells/ml in various concentrations of ITZ or Amp B. Culture densities were examined after 48 hours and IC values to achieve 25%, 50%, and 90% inhibition were determined by comparing to control cells grown in the absence of inhibitors. SD: standard deviations from 3 independent experiments. Ratios of IC (WT)/IC (c14dm−) were indicated.Susceptibility of c14dm− mutants to ITZ and Amp B.
创建时间:
2015-12-02



