The International Council on Harmonization (ICH) S7B and E14 regulatory guidelines are sensitive but not specific for predicting which drugs are pro‐arrhythmic. In response, the Comprehensive In Vitro
Gaining understanding of common complex diseases and their treatments are the main drivers for life sciences. As we show here, comprehensive protein set analyses offer new opportunities to decipher fu
Detecting QT prolongation instances after Dofetilide dosing on the ECGRDVQ dataset; the prevalence for the prolongated QT interval is 25% from the 330 temporal instances.
The version V2.1 is the last update of raw data of the ERBC telemetry database in beagle dogs This new version is is accrued from 22 reference compounds including 15 herg blockers. The list of referen
Some oral anti-hyperglycemic drugs, including gliptins that inhibit dipeptidyl peptidase 4 (DPP4), have been linked to the increased risk of heart failure (HF) in type-2 diabetic patients. While the c
