Effects of different doses of SLV329 in anesthetized rats.
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A bolus of SLV329 followed by an intravenous infusion over 3 hours produces a strong dose-dependent stimulation of renal water, sodium and adenosine excretion without any effect on creatinine clearance. Diuresis and electrolyte excretion is expressed as fold stimulation vs. time-matched vehicle controls.Data are means ± standard error of the mean.n = 9-13 animals per dose.*p**p***p****p
创建时间：
2015-12-02
