Integrative membrane proteome analysis of High and Low-metastatic Lung Cancers

Membrane proteins play critical roles between the tumor cells and the extra-cellular matrix (ECM) during metastasis. In this study, we performed quantitative proteomic analysis of membrane proteins from two human giant-cell lung carcinoma cell strains, low- (95C) and high-(95D) metastatistic cell lines, and combining with microRNA analysis, we identified a multi-omics regulation module.