H2A.Z marks antisense promoters and has positive effects on antisense transcript levels in budding yeast

The histone variant H2A.Z, which has been reported to have both activating and repressive effects on gene expression, is known to occupy nucleosomes at the 5’ ends of protein-coding genes已有研究表明，组蛋白变体H2A.Z（histone variant H2A.Z）可对基因表达兼具激活与抑制双重调控效应，且已知其会定位于蛋白质编码基因5'端的核小体。