Gas chromatography-mass spectrometry separation method of 2-furanyl fentanyl and 3-furanyl fentanyl

A GC-MS method was developed to separate the positional isomers of 2-furanyl fentanyl and 3-furanyl fentanyl. This method is useful to forensic laboratories with limited resources for the routine qualitative detection of either 2- or 3-furanyl fentanyl isomer. The method utilizes a 100% dimethylpolysiloxane stationary phase, 30m x 0.25mm x 0.25µm column with pulsed splitless injection and is able to achieve a resolution of 1.78. Forensic evidentiary samples were run in tandem with samples of the isomeric mixture in which 2-furanyl fentanyl was identified via retention time and mass spectral data. The data files are CSV files of total ion chromatogram data.