five

in silico drug target prediction for melanoma

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https://www.omicsdi.org/dataset/ega/EGAS00001006463
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The in silico single gene deletion step was adapted to simulate the knock-out of all targets of a drug on an objective function such as growth or energy balance. Based on publicly available and in-house large scale transcriptomic data, metabolic models for melanoma were reconstructed, enabling the prediction of 28 candidate drugs and estimating their respective efficacy.EGA study EGAS00001006463
创建时间:
2022-09-19
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