Taking full advantage of PacBio SMRT sequencing used for the genome assembly and detected DNA methylation on a genome-wide scale and analyzing all base modifications to determine modified sequence mot

NIAID Data Ecosystem00

Natural depletion of H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation

转座子调控

DNA甲基化分析

Transposable elements (TEs) are largely inactive. Interestingly, a subset of TEs are naturally expressed in the vegetative cell (VC) of the male gametophyte, pollen in Arabidopsis. However, the extent

NIAID Data Ecosystem00

Clinical and genetic diversity and recurrent CXorf67 mutations across distinct molecular subgroups of posterior fossa type A (PFA) ependymoma.. Clinical and genetic diversity and recurrent CXorf67 mutations across distinct molecular subgroups of posterior fossa type A (PFA) ependymoma.

室管膜瘤分子分型

DNA甲基化分析

Ependymomas are neuroepithelial tumors of the central nervous system (CNS), presenting in both adults and children but accounting for almost 10% of all pediatric CNS tumors and up to 30% of CNS tumors

NIAID Data Ecosystem10

Systemic approaches reveal anti-adipogenic signals at the onset of obesityârelated inflammation in white adipose tissue [ChIP-seq]

肥胖表观遗传学

脂肪组织炎症

HFD feeding induces a rapid adipocyte progenitors (APs) proliferation in visceral adipose tissue (vWAT), followed by a block of differentiation. In contrast, subcutaneous adipose tissue (scWAT), in ob

NIAID Data Ecosystem00

Differentially methylated sites associated with BMI demonstrating characteristic variation of a single blood cell type.

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