Main metabolites found in fecal water of mice over a 33-day study period.

Arrows indicate differences in the spectral profiles between E. caproni-infected mice and non-infected control mice (↑, increased; ↓, decreased in infected animals) and the numbers in brackets show the day post-infection of maximum concentration difference of the respective metabolite. The p-values for the changing metabolites were assessed using a non-parametric 1-way analysis of variance (Mann-Whitney U) test in MATLAB, based on the integrals of the selected peaks and were all in the range of 0.001 to 0.05.