BackgroundMetabolic reprogramming is a well-known hallmark of cancer. Systematical identification of clinically relevant metabolic subtypes of Hepatocellular carcinoma (HCC) is critical to understand
Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12 Descriptor: CITRIC ACID, Complement factor D, Fab20D12 Light Chain, ... Authors: Wu, P, Harris, S.F, Eigenbrot, C. Deposit d
Drug resistance and poor prognosis in acute myeloid leukemia (AML) are major challenges, underscoring the need for effective biomarkers and targeted therapies. In this study, we identified S100A9 as a
The human receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is a critical necroptosis regulator implicated in cancer, psoriasis, ulcerative colitis, rheumatoid arthritis, Alzheimer’s dise
Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST Descriptor: 5-imidazo[1,2-a]pyridin-3-yl-~{N}-[(1~{R})-1-(6-pyrrolidin-1-ylpyridin-
