CIBERSORTx matrices built from mouse kidney single-cell datasets for deconvolution of bulk RNA-Seq data

These are supplementary files from the paper titled "Kidney resident macrophages have distinct subsets and multifunctional roles" [https://doi.org/10.1016/j.matbio.2024.02.002]. These files can be used to enumerate the proportions of 16 cell populations in bulk tissue expression profiles using CIBERSORTx. If you use this dataset, please cite this repository and associated manuscript. Thanks. Label Cell type KRM kidney resident macrophages IM infiltrating monocytes LOH loop of Henle CD collecting duct PT proximal tubule cDC conventional dendritic cells Stroma stromal cells ILC innate lymphoid cells B cells B cells EC endothelial cells NK natural killer cells T cells T cells NP nephron progenitors Basophils basophils Podo podocytes Neutrophils neutrophils File Descriptions File name File type Note CChew_CIBERSORTx_reference_CT1_counts.tsv Single Cell Reference Matrix Raw counts from single-cell RNA sequencing data CChew_CIBERSORTx_pseudobulks_counts.tsv Mixture Raw counts from pseudobulk samples from single-cell RNA sequencing data CChew_CIBERSORTx_sigmatrix.txt Signature Genes Signature matrix file created from the Single Cell Reference Matrix by CIBERSORTx CChew_CIBERSORTx_cell_type_sourceGEP.txt Source GEP Gene expression profile (GEP) matrix for S-mode batch correction