Pyrrolinone–Pyrrolidine Oligomers as Universal Peptidomimetics
收藏NIAID Data Ecosystem2026-03-07 收录
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Peptidomimetics 1–3 were prepared from amino acid-derived tetramic acids 7 as the key starting materials. Calculations show that preferred conformations of 1 can align their side-chain vectors with amino acids in common secondary structures more effectively than conformations of 3. A good fit was found for a preferred conformation of 2 (an extended derivative of 1) with a sheet/β-turn/sheet motif.
创建时间：
2016-02-23
