Tanguay Zebrafish 403 Antiviral Dataset

This dataset contains toxicity screening data for 403 antiviral compounds from the Cayman Antiviral Screening Library evaluated using a dual platform approach combining embryonic zebrafish morphology, mortality, and behavior (ZBEscreen) assessments with the SYSTEMETRIC® Cell Health Screen (CHS).The dataset supports the publication "Accelerating antiviral drug discovery: early hazard detection with a dual zebrafish and cell culture screen of a 403 compound library" (Truong et al., 2025, Archives of Toxicology, DOI: 10.1007/s00204-024-03948-3). This study screened 403 compounds from the Cayman Antiviral Screening Library to identify potential developmental and cytotoxic hazards early in the drug discovery pipeline.