Crystal structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15
收藏Protein Data Bank Japan2025-09-17 更新2026-03-21 收录
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Crystal structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15 Descriptor: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 5-[(5'-{1-(4-carboxy-1,3-thiazol-2-yl)-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-3-yl}-2'-fluoro[1,1'-biphenyl]-4-yl)oxy]-1H-1,2,3-triazole-4-carboxylic acid, ... Authors: Gumpena, R, Ding, J, Powell, D.A, Lowther, W.T. Deposit date: 2021-03-17 Release date: 2021-07-14 Last modified: 2025-09-17 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Characterization of CHK-336, A First-in-Class, Liver-Targeted, Small-Molecule Lactate Dehydrogenase Inhibitor for Hyperoxaluria Treatment. J Am Soc Nephrol, 36, 2025
创建时间：
2021-03-17
