Micro RNA Analysis of the Ossification of Posterior Longitudinal Ligament (OPLL).

Proteomics analysis was conducted using sera from 31 OPLL patients and 17 healthy individuals, detecting a significantly defective protein in the former as compared with the latter. The continuous and mixed types of OPLL were compared, demonstrating a lower level of the protein in the former than the latter. Clinically, the continuous type, i.e., the ossification of the entire longitudinal ligament, was frequently detected in severe cases. The micro-RNA analysis of a healthy and a patient of OPLL of tissue and blood.